פרופ' סלודובניק כותב ומפרסם מאמרים מדעיים בנושא רפואת עור. מאמרים עדכניים:
Role of Patch Testing in Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is a common debilitating condition. Although not completely understood, the main pathomechanism involves autoimmune-related mast-cell degranulation. Patch test (PT) is the gold standard for the diagnosis of type IV cutaneous hypersensitivity. The relevance of PT to the diagnosis of CSU is debatable.
Occupational factors in skin diseases
A significant proportion of our lives is spent at work, and thus environmental factors are of great importance. Work-related skin conditions have become one of the leading causes of occupational diseases impacting on individuals, society and the economy. We discuss important occupational skin diseases and also occupational aggravation of pre-existing skin conditions. Chemical, physical and mechanical causes are discussed as well. We believe that better understanding of these conditions would result in improved strategies for prevention and better risk management.
Irritant contact dermatitis: a review
Irritant contact dermatitis is the most common form of contact dermatitis, and yet is often overlooked. Recent progress in understanding the pathogenesis has reignited the interest of clinicians in this area of dermatology. Irritant contact dermatitis is not a homogenous entity, but rather a number of subtypes contributing to different clinical presentations. The diagnosis of irritant contact dermatitis is often clinical, and may only be possible after the exclusion of allergic contact dermatitis with patch testing. There is no readily available diagnostic test. There is an incomplete understanding of the factors which lead to the development of cumulative irritant contact dermatitis and persistent postoccupational dermatitis. We have used the experience from our tertiary referral occupational dermatology clinic to illustrate various aspects of irritant contact dermatitis, and to highlight the difficulty sometimes encountered in making this diagnosis. We believe that increased awareness of the often pivotal role of irritant contact dermatitis, as well as all the other factors contributing to occupational dermatitis, will lead to improvement in outcomes for patients.